Figure 1.
Summary of metabolic and epigenetic alterations induced by IDH mutations in cancer cells. The action mode of inhibitors targeting the mutant isocitrate dehydrogenase (IDH) proteins is indicated.
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.