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. 2018 Nov 29;10(3):1729–1743. doi: 10.1021/acschemneuro.8b00620

Table 4. Rodin-A Toxicokinetic Parameters in Rats and Dogs Following Repeated Daily Oral Administration for 14 Days.

	SD rat^a			beagle dog^b
	30 mg/kg	45 mg/kg	60 mg/kg	45 mg/kg	60 mg/kg	120 mg/kg
C_max (ng/mL)
day 14	1670 ± 184	3780 ± 1450	3760 ± 1160	6283 ± 1510	10100 ± 4730	18600 ± 7410
AUC (ng·h/mL)
day 14	8240 ± 1940	13200 ± 4760	28700 ± 7570	11487 ± 1918	13000 ± 5790	25000 ± 14300

^a

Two animals per group; value reported is the mean ± SD.

^b

Three animals per group; value reported is the mean ± SD.