Table 1.
Tissue donor and tumor characteristics according to subtype.
| Characteristics | HR+/HER2+ (n = 20) |
HR+/HER2− (n = 20) |
HR−/HER2+ (n = 21) |
HR−/HER2− (TNBC) (n = 20) |
P |
|---|---|---|---|---|---|
| Age (mean ± SD) | 55.75 ± 13.32 | 56.45 ± 14.24 | 58.24 ± 11.48 | 55.90 ± 11.63 | 0.9183 1 |
| Max. tumor dimension (mean ± SD) | 2.26 ± 1.18 | 4.36 ± 3.29 | 2.51 ± 1.52 | 2.47 ± 0.96 | 0.0019 1 |
| Histological grade 2 | 0.0002 3 | ||||
| I | 0 | 4 | 0 | 1 | |
| II | 15 | 8 | 6 | 3 | |
| III | 5 | 7 | 15 | 15 | |
| Tumor stage 2 | 0.0009 3 | ||||
| T1 | 12 | 1 | 9 | 8 | |
| T2 | 6 | 15 | 11 | 11 | |
| T3 | 0 | 4 | 0 | 0 | |
| T4 | 2 | 0 | 1 | 0 | |
| Nodal stage 2 | 0.1181 3 | ||||
| N0 | 12 | 8 | 10 | 12 | |
| N1 | 4 | 4 | 6 | 4 | |
| N2 | 3 | 4 | 4 | 2 | |
| N3 | 0 | 4 | 0 | 0 | |
| Clinical stage 2 | 0.0316 3 | ||||
| I | 7 | 0 | 7 | 4 | |
| II | 8 | 11 | 9 | 13 | |
| III | 4 | 9 | 5 | 2 | |
| Ever smoked 2 | 0.0588 3 | ||||
| Yes | 1 | 7 | 4 | 7 | |
| No | 8 | 12 | 9 | 3 | |
| Menopausal status 2 | 0.5140 3 | ||||
| Pre-menopause | 7 | 4 | 4 | 4 | |
| Post-menopause | 10 | 11 | 17 | 10 |
1 ANOVA; 2 Data not available for all samples; 3 Chi-square test using available data.