Table 3.
Predictors of primary and secondary endpoints in Cox regression analysis.
| Predictors | Model 1 a | Model b | Model c | ||
|---|---|---|---|---|---|
| Primary end point | Chemerin level subgroups d | Hazard ratio (95% CI) | 5.71 (2.62–12.48) | 4.55 (1.86–11.16) | 3.55 (1.46–8.68) |
| p value | <0.0001 | 0.001 | 0.005 | ||
| CRP level subgroups e | Hazard ratio (95% CI) | 7.82 (3.66–16.71) | 5.73 (2.39–13.75) | 4.27 (1.72–10.61) | |
| p value | <0.0001 | <0.0001 | 0.002 | ||
| Combined risk subgroups (intermediate vs. low) |
Hazard ratio (95% CI) | 2.61 (0.97–7.00) | 2.72 (0.94–7.93) | 1.85 (0.62–5.53) | |
| p value | 0.057 | 0.063 | 0.275 | ||
| Combined risk subgroups | Hazard ratio (95% CI) | 17.02 (7.04–41.13) | 11.17 (3.84–32.47) | 8.71 (2.99–25.31) | |
| (high vs. low) | p value | <0.0001 | <0.0001 | <0.0001 | |
| Secondary end point | Chemerin level subgroups | Hazard ratio (95% CI) | 4.44 (2.59–7.60) | 3.78 (2.11–6.76) | 3.04 (1.69–5.47) |
| p value | <0.0001 | <0.0001 | 0.0002 | ||
| CRP level subgroups | Hazard ratio (95% CI) | 4.84 (2.72–8.60) | 3.78 (2.02–7.07) | 2.76 (1.45–5.25) | |
| p value | <0.0001 | <0.0001 | 0.002 | ||
| Combined risk subgroups | Hazard ratio (95% CI) | 3.82 (2.07–7.05) | 4.14 (2.17–7.89) | 3.18 (1.64–6.18) | |
| (intermediate vs. low) | p value | <0.0001 | <0.0001 | 0.001 | |
| Combined risk subgroups | Hazard ratio (95% CI) | 9.47 (4.70–19.06) | 5.87 (2.67–12.93) | 4.52 (2.04–10.03) | |
| (high vs. low) | p value | <0.0001 | <0.0001 | 0.0002 |
95% CI: 95% confidence interval a Model 1: Unadjusted. b Model 2: Adjusted for baseline data (sex, age, BMI, current smoking status, diabetes mellitus, hypertension, and dyslipidemia). c Model 3: Adjusted for baseline data and initial presentation (sex, age, BMI, current smoking status, diabetes mellitus, hypertension, dyslipidemia, and initial presentation). d Chemerin level subgroups: >163.8 ng/mL vs. ≤163.8 ng/mL of chemerin level. e CRP level subgroups: >9.7 mg/L vs. ≤9.7 mg/L of CRP level.