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. 2019 Feb 26;24(5):834. doi: 10.3390/molecules24050834

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© 2019 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Melt electrospun scaffolds and their effects on human hematopoietic stem cells. (A) Melt electrospun PCL scaffolds. (B) Scanning electron microscopy (SEM) image of primary human osteoblasts on scaffolds in osteogenic conditions. (C) Cross-section profiles of scaffolds seeded with primary human osteoblasts in osteogenic conditions. (D–G) The expression of (D) fibronectin (FN), (E) vitronectin (VN), (F) Alkaline phosphatase (ALP), and (G) osteopontin (OPN) by primary human osteoblasts in osteogenic conditions. (H) Confocal microscopy showed that CD45⁺ cells (green) attached and migrated into primary human osteoblast-seeded scaffolds using osteogenic conditions (red); cell nuclei in blue. Reproduced from [154] with permission from Elsevier Ltd.; Copyright 2017.