Table 8.
Feature importances for each chemical component as derived by the SKATER algorithm for the RP62A/inhibition, O-47/inhibition, 6538P/activation and 259237/activation optimized models at 3.125 mg/mL. Background of more important chemical component for inhibition are colored in darker green, while in darker red background are highlighted components associated to higher biofilm production enhancement.
| Chemical Component | Biofilm Inhibition Models | Biofilm Inhibition Models | ||
|---|---|---|---|---|
| RP62A | O-47 | 6538P | 25923 | |
| 2-Hydroxypiperitenone | 0.23 | 0.32 | 0.38 | 0.44 |
| 2,3-Pinanediol | 1.33 | 4.07 | 1.47 | 1.05 |
| 3-Methylcyclohexanone | 0.16 | 0.45 | 1.09 | 1.62 |
| 3-Octanol | 6.47 | 7.16 | 10.80 | 4.44 |
| 4-Terpineol | 1.99 | 1.81 | 3.65 | 3.57 |
| α-Phellandrene | 0.61 | 0.30 | 3.02 | 0.67 |
| α-Pinene | 2.71 | 2.98 | 1.00 | 0.21 |
| α-Terpineol | 2.40 | 3.32 | 2.81 | 2.22 |
| Apiol | 0.17 | 0.78 | 0.83 | 0.97 |
| β-Cymene | 1.46 | 1.35 | 2.42 | 6.37 |
| β-Linalool | 1.40 | 1.08 | 0.93 | 7.08 |
| β-Myrcene | 0.72 | 0.05 | 0.95 | 0.67 |
| β-Ocimene | 0.56 | 1.75 | 0.78 | 0.06 |
| β-Phellandrene | 1.62 | 5.42 | 3.30 | 0.69 |
| β-Pinene | 1.31 | 1.15 | 0.34 | 2.12 |
| β-Terpinene | 0.17 | 0.63 | 0.97 | 0.15 |
| Borneol | 0.07 | 0.25 | 0.45 | 0.56 |
| Carvacrol | 0.38 | 0.38 | 0.34 | 0.26 |
| Caryophyllene | 1.35 | 1.67 | 2.78 | 4.36 |
| Caryophyllene oxide | 0.13 | 1.23 | 0.32 | 3.25 |
| Chrysanthenone | 3.87 | 3.58 | 2.68 | 4.79 |
| Cinerolone | 1.14 | 0.40 | 0.64 | 1.45 |
| cis-β-Terpineol | 0.55 | 0.55 | 0.88 | 1.85 |
| cis-Sabinol | 4.60 | 3.40 | 4.36 | 0.17 |
| Citral | 0.12 | 0.39 | 0.65 | 0.99 |
| Cryptone | 0.15 | 1.63 | 0.09 | 0.27 |
| d-Limonene | 5.66 | 6.29 | 9.22 | 1.56 |
| delta-Cadinene | 1.62 | 0.90 | 0.40 | 1.17 |
| Estragole | 3.87 | 3.21 | 0.04 | 2.49 |
| Fenchone | 3.66 | 3.08 | 0.06 | 1.54 |
| γ-Terpinene | 0.19 | 1.14 | 1.51 | 1.97 |
| Germacrene D | 0.82 | 0.65 | 0.65 | 0.14 |
| Isocaryophyllene | 0.86 | 0.58 | 0.84 | 0.07 |
| Isomenthone | 1.53 | 0.26 | 0.71 | 1.77 |
| Isopiperitenone | 2.80 | 2.38 | 1.61 | 2.42 |
| Isopulegone | 0.01 | 0.63 | 4.89 | 0.85 |
| Limonene | 1.64 | 4.02 | 2.62 | 0.67 |
| Menthol | 2.17 | 1.30 | 1.38 | 7.16 |
| Menthone | 3.00 | 3.07 | 3.81 | 7.51 |
| Methyl isopulegone | 0.27 | 0.14 | 0.27 | 0.13 |
| Myristicin | 4.16 | 2.48 | 0.16 | 0.59 |
| o-Cymene | 2.64 | 6.40 | 3.44 | 1.62 |
| p-Cymen-8-ol | 0.90 | 1.76 | 0.89 | 0.96 |
| p-Cymene | 2.99 | 0.02 | 0.39 | 1.14 |
| p-Menth-1(7)-en-2-one | 5.06 | 0.89 | 1.51 | 0.91 |
| p-Menthene | 0.43 | 0.33 | 0.26 | 0.35 |
| Phellandral | 6.15 | 3.97 | 1.40 | 2.08 |
| Piperitenone | 0.21 | 0.03 | 2.86 | 4.95 |
| Piperitenone oxide | 2.32 | 0.46 | 1.68 | 0.36 |
| Pulegone | 4.06 | 4.10 | 9.12 | 4.18 |
| Sabinene | 0.61 | 0.62 | 0.91 | 0.62 |
| Terpinolene | 0.55 | 1.90 | 1.07 | 1.84 |
| Thymol | 5.73 | 2.94 | 0.08 | 0.31 |
| trans-p-Mentha-2,8-dienol | 0.43 | 0.33 | 0.26 | 0.35 |