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Expression of aggrecan in cartilage of mice carrying the CreERT2 transgene. (A) relative gene expression of Agc1 in newborn rib cartilage primary chondrocytes of Agc1+/+, Agc1CreERT2/+ and Agc1CreERT2/CreERT2, mice. The mean values ± SD from three independent animals of each genotype are shown; (B) sagittal sections of the knee joint were stained with antibodies against aggrecan, collagen type II, and with Toluidine blue. n = 5 mice per genotype.
