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. 2019 Feb 27;20(5):1029. doi: 10.3390/ijms20051029

Figure 1.

Figure 1

Schematic representation of SETD2 mutations associated with hematopoietic malignancies. Mutations are represented according to type. The following hematopoietic malignancies are represented: Activated B-cell type, acute lymphoid leukemia, acute myeloid leukemia, B-lymphoblastic leukemia/lymphoma, chronic lymphocytic leukemia, diffuse large B-cell lymphoma and germinal center B-cell type leukemia. Duplicates were removed. SETD2 domains: AWS, associated with SET; SET, Su(var)3-9, enhancer-of-zeste trithorax; PS, post-SET; CC, coiled coil; WW, rsp5-domain; SRI, Set2 Rpb1 interacting. Mutation data were retrieved from cBioPortal (http://www.cbioportal.org) on 27 November 2018.