Table 1.
Patients Characteristics.
Patients Characteristics | All Patients | With CSF | Without CSF | P Value (Uncorrected) |
---|---|---|---|---|
No of patients | 188 | 77 | 111 | |
Age, median (range) | 50 (15-92) | 54 (16-82) | 48 (15-92) | .51 |
Female, n (%) | 141 (75%) | 63 (81%) | 78 (70%) | .09 |
Precipitants of PRES, n (%) | ||||
Hypertension | 166 (89%) | 69 (87%) | 97 (90%) | .60 |
Immunosuppressiona | 66 (34%) | 32 (41%) | 34 (31%) | .17 |
Sepsis | 31 (16%) | 14 (18%) | 17 (16%) | .70 |
Autoimmune disease | 25 (13%) | 12 (15%) | 13 (12%) | .50 |
Pregnancy/eclampsia | 32 (17%) | 11 (14%) | 21 (19%) | .35 |
Other thrombotic microangiopathy | 11 (6%) | 4 (5%) | 7 (6%) | .70 |
Symptoms of PRES, n (%) | ||||
Seizure | 115 (61%) | 49 (62%) | 66 (61% | .94 |
Encephalopathy | 108 (58%) | 47 (59%) | 61 (56%) | .68 |
Headache | 80 (43%) | 35 (44%) | 45 (42%) | .72 |
Vision changes | 49 (26%) | 17 (22%) | 32 (29%) | .24 |
Other | 25 (13%) | 10 (13%) | 15 (14%) | .85 |
Hospital LOS, days, median (range) | 10 (2-135) | 11 (2-70) | 10 (2-135) | .67 |
Hospital disposition, n (%) | .87 | |||
Home | 120 (64%) | 51 (65%) | 69 (63%) | |
Facility | 57 (30%) | 23 (30%) | 34 (30%) | |
Died | 9 (5%) | 3 (4%) | 6 (6%) |
Abbreviations: CSF, cerebrospinal fluid; LOS, length of stay; PRES, posterior reversible encephalopathy syndrome.
a Includes immunosuppressive and chemotherapeutic medications