. 2019 Mar 21;16:E33. doi: 10.5888/pcd16.180405

Table. Results of Global and Local Moran’s I Analysis for Overdose Mortality Rates, United States, 2000–2016.

Variable	Univariate^a				Bivariate^b			Differential^c
Variable	2000	2010	2014	2016	2010 and Burden	2014 and Rent Burden	2016 and Burden	2000 and 2016
Moran’s I	0.114^d	0.098^d	0.133^d	0.231^d	0.081^d	0.112^d	0.145^d	0.114^d
No. of high–high clusters	102	132	200	265	230	254	160	104
No. of low–low clusters	547	505	549	693	487	500	441	174
No. of high–low clusters	39	55	65	72	64	67	67	43
No. of low–high clusters	220	177	200	164	228	197	169	218

Univariate Moran’s I identifies significant outlier clusters of areas with high age-adjusted drug overdose mortality rates surrounded by other areas of high age-adjusted drug overdose mortality rates.

Bivariate Moran’s I identifies significant outlier clusters of areas with high age-adjusted drug overdose mortality rates surrounded by other areas of high percentages of populations who contribute greater than 50% of their income to rent.

Differential Moran’s I identifies significant outlier clusters of areas with high 2016 age-adjusted drug overdose mortality rates surrounded by other areas of high age-adjusted drug overdose mortality rates in 2000.

P < .05.