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Comparison of copy number alterations: The CNV patterns were similar among primary (blue), pre-FOLFOX metastatic (purple), and post-FOLFOX metastatic (red) tumor samples in all cases. The x-axis coordinates represent positions along the genome; the vertical bars indicate the borders between chromosomes. The y-axis represents the chromosomal copy number in the tumor compared to normal tissues. A log ratio greater than two was considered significant copy number amplification
