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. 2019 Mar 21;19:253. doi: 10.1186/s12885-019-5455-1

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Bortezomib inhibition of the proteasome in PANC-1 cells results in decreased viability and cell death. a Bortezomib dosage in PANC-1 cells and percentage viability after 96 h of treatment. b Representative flow cytometry panels of PANC-1 cells and c quantification of PANC-1 cells and Mia PaCa-2 cells treated with 1 nM bortezomib for 48 h then stained with 7-AAD and Annexin V to assess cell apoptosis. (*P = 0.05, **P = 0.01; ****P = 0.0001)