Fig. 2.

LMW-PTP knockdown results in enhanced Mec-1 cell apoptosis. a, b Flow cytometric analysis of the percentages of Annexin V⁺/PI⁻ in Mec-1 cell silenced (siRNA) or not for LMW-PTP, treated with either DMSO or 3.5 µM fludarabine (a) or 0.1 µM ibrutinib (b) for 24 h. Data are expressed as the mean values ± SD determined from three independent experiments. ***p ≤ 0.001, **p ≤ 0.01