Table 4.
Time to radiographic progression
| Abiraterone Acetate + Prednisone | |
|---|---|
| All enrolled patients | 131 |
| Radiographic progression event | 31 (23.7) |
| Censored | 100 (76.3) |
| Time to radiographic progression event | |
| Median (95% Cl) | NE (41.4, NE) |
| Range | (0.0+, 49.8+) |
| Progression-free rates, n | 131 |
| 12 months (95% Cl) | 0.862 (0.782, 0.915) |
| 24 months (95% Cl) | 0.746 (0.645, 0.822) |
| 36 months (95% Cl) | 0.691 (0.582, 0.776) |
| 48 months (95% Cl) | 0.615 (0.470, 0.732) |
| Sensitivity analysis* | Abiraterone Acetate + Prednisone |
| All enrolled patients | 131 |
| Radiographic progression event | 46 (35.1) |
| Censored | 85 (64.9) |
| Time to radiographic progression event | |
| Median (95% Cl) | 41.4 (27.6, NE) |
| Range | (0.0+, 49.8+) |
| Progression-free rates, n | 131 |
| 12 months (95% Cl) | 0.810 (0.723, 0.872) |
| 24 months (95% Cl) | 0.665 (0.564, 0.747) |
| 36 months (95% Cl) | 0.553 (0.445, 0.648) |
| 48 months (95% Cl) | 0.492 (0.367, 0.606) |
= censored observation; NE = not estimable.
Sensitivity analysis includes events that were not confirmed by a second scan due to patient or physician decision.