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. Author manuscript; available in PMC: 2019 Aug 1.
Published in final edited form as: J Urol. 2018 Apr 6;200(2):344–352. doi: 10.1016/j.juro.2018.03.125

Table 4.

Time to radiographic progression

Abiraterone Acetate + Prednisone
All enrolled patients 131
 Radiographic progression event 31 (23.7)
 Censored 100 (76.3)
Time to radiographic progression event
 Median (95% Cl) NE (41.4, NE)
 Range (0.0+, 49.8+)
Progression-free rates, n 131
 12 months (95% Cl) 0.862 (0.782, 0.915)
 24 months (95% Cl) 0.746 (0.645, 0.822)
 36 months (95% Cl) 0.691 (0.582, 0.776)
 48 months (95% Cl) 0.615 (0.470, 0.732)
Sensitivity analysis* Abiraterone Acetate + Prednisone
All enrolled patients 131
 Radiographic progression event 46 (35.1)
 Censored 85 (64.9)
Time to radiographic progression event
 Median (95% Cl) 41.4 (27.6, NE)
 Range (0.0+, 49.8+)
Progression-free rates, n 131
 12 months (95% Cl) 0.810 (0.723, 0.872)
 24 months (95% Cl) 0.665 (0.564, 0.747)
 36 months (95% Cl) 0.553 (0.445, 0.648)
 48 months (95% Cl) 0.492 (0.367, 0.606)
+

= censored observation; NE = not estimable.

*

Sensitivity analysis includes events that were not confirmed by a second scan due to patient or physician decision.