Table 3.
The top 20 most gained dipeptides from p53 mutations.
| Dipeptide pairs | Number lost | Number gained | Dipeptide propensity | |
|---|---|---|---|---|
| p53 | p63/p73 | |||
| V/H | 0 | 16222 | 2.469 | 3.843 |
| R/H | 170 | 1424 | 3.984 | 3.451 |
| V/C | 231 | 1321 | 3.788 | 3.255 |
| R/W | 0 | 1308 | 0.098 | 1.302 |
| H/C | 0 | 1262 | 1.491 | 2.367 |
| R/Q | 0 | 966 | 2.649 | 7.407 |
| N/Q | 0 | 834 | 3.231 | 5.94 |
| N/W | 0 | 714 | 2.043 | 1.314 |
| P/S | 99 | 674 | 7.783 | 11.639 |
| V/L | 2 | 654 | 4.767 | 7.052 |
| S/G | 119 | 652 | 7.685 | 5.71 |
| F/R | 195 | 638 | 5.11 | 3.835 |
| R/S | 3 | 635 | 4.71 | 3.226 |
| M/S | 0 | 626 | 1.417 | 5.092 |
| L/R | 184 | 584 | 4.198 | 3.102 |
| D/W | 0 | 552 | 1.147 | 1.029 |
| E/C | 0 | 497 | 1.225 | 1.415 |
| E/R | 149 | 429 | 5.706 | 2.61 |
| L/P | 54 | 415 | 7.567 | 5.882 |
| P/C | 929 | 412 | 7.29 | 6.391 |
| Average | 106.75 | 810.95 | 3.9179 | 4.2931 |
| Statistical differencesa of dipeptide propensity between the lost and gain groups P = 0.04 | Statistical differencesa between p53 and p63/p73 P = 0.2225 | |||
a
Student test of the significance of the difference.