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. 2019 Mar 15;9(3):e024159. doi: 10.1136/bmjopen-2018-024159

Table 1.

Association between patient demographic and sites, and the use of low molecular weight heparin (LMWH) for venous thromboembolism (VTE) prophylaxis and not using albumin for fluid resuscitation

Appropriate VTE prophylaxis
OR (95% CI)*
Appropriate fluid resuscitation
OR (95% CI)†
Age NS‡ 0.999 (0.999 to 1.00)
Female NS‡ NS‡
Any comorbidity NS‡ NS‡
Admission type
 Elective surgery 1.00 (reference group) 1.00 (reference group)
 Emergent surgery 1.19 (0.92 to 1.53) 0.92 (0.88 to 0.95)
 No surgery 1.34 (1.08 to 1.66) 1.02 (0.98 to 1.05)
APACHE II score (ICU admission) 0.958 (0.951 to 0.965) 0.989 (0.988 to 0.990)
Site
 C1 1.00 (reference group) 1.00 (reference group)
 C2 1.32 (1.07 to 1.64) 0.96 (0.92 to 1.00)
 C3 1.13 (0.89 to 1.46) 0.98 (0.94 to 1.03)
 C4 1.48 (1.15 to 1.90) 0.98 (0.93 to 1.02)
 E1 2.12 (1.66 to 2.73) 0.90 (0.86 to 0.95)
 E2 0.86 (0.71 to 1.05) 0.90 (0.87 to 0.92)
 E3 7.26 (5.46 to 9.65) 0.92 (0.87 to 0.97)
 E4 0.76 (0.63 to 0.92) 0.88 (0.85 to 0.91)
 E5 1.61 (1.23 to 2.10) 0.75 (0.72 to 0.79)

All ‘C’ sites indicate intensive care unit (ICU) in Calgary and all ‘E’ sites indicate ICU in Edmonton.

*Multivariable generalised estimating equations logistic regression model with exchangeable correlation structure given daily measurements (clustering by patient); ‘appropriate’ considered use of LMWH.

†Standard multivariable logistic regression model given single measurement per patient; ‘appropriate’ considered not using albumin.

‡NS=non significant, removed from model.