Table 3.
hMAM expression in the breast cancer tissue and blood according to different characteristics
| Characteristics | Cases (n) | hMAM (+) in breast cancer tissues | hMAM (+) in peripheral blood of breast cancer patients | ||||
|---|---|---|---|---|---|---|---|
|
| |||||||
| n | % | P-value | n | % | P-value | ||
|
| |||||||
| Age (years) | |||||||
| ≤50 | 21 | 16 | 76.2 | 0.19 | 10 | 47.6 | 0.45 |
| >50 | 22 | 20 | 90.9 | 13 | 59.1 | ||
| Tumor size | |||||||
| T1 | 10 | 9 | 90.0 | 0.50 | 3 | 30.0 | 0.02 |
| T2 | 17 | 13 | 76.5 | 7 | 41.2 | ||
| T3 and T4 | 16 | 14 | 87.5 | 13 | 81.2 | ||
| Distant metastasis | |||||||
| M0 | 38 | 31 | 81.6 | 0.29 | 18 | 47.4 | 0.03 |
| M1 | 5 | 5 | 100.0 | 5 | 100.0 | ||
| Lymph node | |||||||
| No | 13 | 10 | 76.9 | 0.40 | 5 | 38.5 | 0.19 |
| Yes | 30 | 26 | 86.7 | 18 | 60.0 | ||
| Stage of cancer | |||||||
| I | 8 | 7 | 87.5 | 0.75 | 2 | 25.0 | 0.01 |
| II | 19 | 15 | 78.9 | 8 | 42.1 | ||
| III and IV | 16 | 14 | 87.5 | 13 | 81.2 | ||
| Histopathology type | |||||||
| Ductal | 29 | 27 | 93.1 | 0.06 | 16 | 55.2 | 0.52 |
| Lobular | 8 | 5 | 62.5 | 3 | 37.5 | ||
| Mucus | 6 | 4 | 66.7 | 4 | 66.7 | ||
| CA15-3 (U/mL) | |||||||
| ≤32 | 33 | 29 | 84.4 | 0.50 | 16 | 48.5 | 0.23 |
| >32 | 10 | 7 | 70.0 | 7 | 70.0 | ||
Abbreviation: hMAM, human mammaglobin mRNA.