Table 3.
The antimicrobial resistance profile of 44 Klebsiella pneumoniae strains from cerebrospinal fluid
| Antimicrobials | No. (%) of resistant isolates | P-value (hvKP vs non-hvKP) | ||
|---|---|---|---|---|
| Total (n=44) | hvKP (n=22) | Non-hvKP (n=22) | ||
| Ampicillin–sulbactam | 35 (79.5) | 17 (77.3) | 18 (81.8) | 1.00 |
| Piperacillin–tazobactam | 29 (65.9) | 15 (68.2) | 14 (63.6) | 0.75 |
| Ceftazidime | 29 (65.9) | 13 (59.1) | 16 (72.7) | 0.34 |
| Ceftriaxone | 34 (77.3) | 17 (77.3) | 17 (77.3) | 1.00 |
| Cefepime | 27 (61.4) | 13 (59.1) | 14 (63.6) | 0.76 |
| Aztreonam | 32 (72.7) | 16 (72.7) | 16 (72.7) | 1.00 |
| Ertapenem | 29 (65.9) | 15 (68.2) | 14 (63.6) | 0.75 |
| Imipenem | 28 (63.6) | 15 (68.2) | 13 (59.1) | 0.53 |
| Amikacin | 15 (34.1) | 10 (45.5) | 5 (22.7) | 0.11 |
| Gentamicin | 21 (47.7) | 10 (45.5) | 11 (50.0) | 0.76 |
| Tobramycin | 17 (38.6) | 10 (45.5) | 7 (31.8) | 0.35 |
| Ciprofloxacin | 26 (59.1) | 13 (59.1) | 13 (59.1) | 1.00 |
| Levofloxacin | 24 (54.5) | 13 (59.1) | 11 (50.0) | 0.55 |
| Trimethoprim–sulfamethoxazole | 17 (38.6) | 9 (40.9) | 8 (36.4) | 0.76 |
| Tigecycline | 0 (0.0) | 0 (0.0) | 0 (0.0) | – |
| Colistin | 0 (0.0) | 0 (0.0) | 0 (0.0) | – |
Abbreviations: hvKP, hypervirulent K. pneumonia; non-hvKP, non-hypervirulent K. pneumonia.