Table 2.
Significantly activated brain regions.
| Contrasts of interest | MNI Coordinates |
Z-scores | T values | P values | ||
|---|---|---|---|---|---|---|
| X | Y | Z | ||||
| BPD patients vs Healthy subjects | ||||||
| Life event resolved condition vs life event neutral condition | ||||||
| Right prefrontal cortex (rMPFC) | 11 | 51 | 9 | 4.09 | 4.28 | = .001 |
| Right anterior insula (rAI) | 48 | 25 | 4 | 4.10 | 4.32 | <.001 |
| Left anterior insula (lAI) | -43 | 21 | 7 | 4.05 | 4.24 | = .002 |
| Right dorsolateral prefrontal cortex (rDLPFC) | 35 | 28 | 31 | 4.07 | 4.27 | = .001 |
| Right anterior cingulate cortex (rACC) | 7 | 42 | 14 | 4.02 | 4.23 | = .002 |
| Life event unresolved condition vs life event neutral condition | ||||||
| Right anterior cingulate cortex (rACC) | 8 | 39 | 12 | 4.39 | 4.46 | <.001 |
| Left anterior cingulate cortex (lACC) | -10 | 29 | 12 | 3.89 | 3.81 | = .002 |
| Right dorsolateral prefrontal cortex (rDLPFC) | 41 | 17 | 30 | 4.01 | 4.15 | = .003 |
| Left dorsolateral prefrontal cortex (lDLPFC) | -37 | 19 | 26 | 4.47 | 4.67 | <001 |
| Right temporal parietal junction (rTPJ) | 42 | -56 | 34 | 3.96 | 3.86 | = .002 |
Peak activity coordinates are given in MNI space.
Significant neural activation in group analysis: patient group vs control group for the contrasts 1) life event resolved condition vs life event neutral condition, and 2) life event unresolved condition vs life event neutral condition.
All contrasts were analysed using a small volume correction (SVC) with a sphere of 10 mm radius Statistical threshold of p < .004 family-wise error corrected for multiple comparisons at the voxel level over small volumes of interest.