Table 2.

Study timeline including randomisation, enrolment and follow-up visits

Timepoint	Allocation	Enrolment	Study period
			Postallocation							Close-out
		0	ANC visit*				Postnatal care visits
			1	2	3	4	6 weeks	14 weeks	6 months	9 months
Enrolment
Facility allocation	X
Eligibility screen		X
Informed consent		X
Interventions
Universal PrEP offer		U
Risk score guided PrEP offer		T
Self-test kit distribution		T
PrEP refill			P	P	P	P	P	P	P	P
Assessments
Demographic		X					X			X
Medical		X					X			X
Psychosocial		X					X			X
Partner characteristics		X					X			X
Risk assessment		X	X	X	X	X	X	X	X	X
HIV testing		X	X	X	X	X	X	X	X	X
Birth and infant growth outcomes							X	X	X	X
DBS for adherence			P	P	P	P	P	P	P	P

*Number of ANC visits depends on gestational age at enrolment.

ANCA, antenatal care; DBS, dried blood spots; P, PrEP users; PrEP, pre-exposure prophylaxis; T, targeted arm participants only; U, universal arm participants only; X, all study participants.