Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Sep 23;6(10):1840–1851. doi: 10.1002/sctm.17-0028

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2017 The Authors stem cells translational medicine published by Wiley Periodicals, Inc. on behalf of AlphaMed Press

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

PMC Copyright notice

Quantification of mesenchymal perivascular cells localization by image analysis in early progressive MS (EPMS) and late stage progressive MS (LPMS). Quantification of immunohistochemical staining for mesenchymal stromal cells/pericyte markers using generalized estimating equations demonstrated significant changes in mean pixel area ratio (fold‐change) stained between different MS tissue types and healthy, and demyelinating disease and healthy. A significant difference in marker detection between EPMS and LPMS tissues was also apparent. (A): CD146, (B): PDGFRβ, (C): CD73, and (D): CD271. Detailed numbers pertaining to the significance can be found in Supporting Information Table 3. p values a = ≤.001, b = ≤.005, c = ≤.01, and d = ≤ .05. The dotted line indicates the normalized value (1) of healthy tissue. Abbreviations: NAWM, normal‐appearing white matter; PDGFRβ, platelet‐derived growth factor receptor beta.