Table 1.
Associations of miR-328-3p expression with various clinicopathological characteristics of primary osteosarcoma
| Clinicopathological characteristics | No. of patients (n, %) | miR-328-3p low (%) | P-value |
|---|---|---|---|
| Age (years) | |||
| <20 | 38 (43.18) | 20 (52.64) | NS |
| ≥20 | 50 (56.82) | 25 (50.00) | |
| Gender | |||
| Male | 52 (59.09) | 29 (55.77) | NS |
| Female | 36 (40.91) | 16 (44.44) | |
| Tumor size (cm) | |||
| ≤5 | 40 (45.45) | 20 (50.00) | NS |
| >5 | 48 (54.55) | 25 (52.08) | |
| Tumor location | |||
| Femur | 46 (52.27) | 21 (45.65) | NS |
| Tibia | 20 (22.73) | 12 (60.00) | |
| Humerus | 18 (20.45) | 10 (55.56) | |
| Fibula | 4 (4.55) | 2 (50.00) | |
| Surgical stage | |||
| IIA | 33 (37.50) | 10 (30.30) | 0.01 |
| IIB/III | 55 (62.50) | 35 (63.64) | |
| Metastasis | |||
| No | 53 (60.23) | 13 (24.53) | 0.008 |
| Yes | 35 (39.77) | 32 (91.43) | |
| Recurrence | |||
| No | 54 (61.36) | 20 (37.04) | 0.01 |
| Yes | 34 (38.64) | 25 (73.53) | |
| Histological subtype | |||
| Osteoblastic | 54 (61.36) | 35 (64.81) | NS |
| Chondroblastic | 18 (20.45) | 6 (33.33) | |
| Fibroblastic | 11 (12.50) | 2 (18.18) | |
| Mixed type | 3 (3.41) | 2 (66.67) | |
| Small type | 2 (2.27) | 0 (0.00) | |
Abbreviations: miR, microRNA; NS, Not significant.