Table 5.
Correlation between microRNA expression level and clinical pathological parameters in breast cancer patients
| Parameters | Total (n) | MicroRNA score | P-value | |
|---|---|---|---|---|
| Low (n=120) | High (n=133) | |||
| Age, years | 0.791 | |||
| ≤45 | 53 | 26 (21.7) | 27 (20.3) | |
| >45 | 200 | 94 (78.3) | 106 (79.7) | |
| Missing (%) | 0 | |||
| ER (%) | 0.723 | |||
| Negative | 66 | 30 (45.5) | 36 (54.5) | |
| Positive | 177 | 85 (48.0) | 92 (52.0) | |
| Missing | 10 | |||
| PR (%) | 0.778 | |||
| Negative | 91 | 42 (46.2) | 49 (53.8) | |
| Positive | 152 | 73 (48.0) | 79 (52.0) | |
| Missing | 10 | |||
| Her2 (FISH) (%) | 0.343 | |||
| Negative | 197 | 96 (48.7) | 101 (51.3) | |
| Positive | 35 | 14 (40.0) | 21 (60.0) | |
| Missing | 21 | |||
| T stage (%) | 0.177 | |||
| T1 | 65 | 29 (44.6) | 36 (55.4) | |
| T2 | 133 | 59 (44.4) | 74 (55.6) | |
| T3 | 38 | 22 (57.9) | 16 (42.1) | |
| T4 | 14 | 8 (57.1) | 6 (42.9) | |
| Missing | 3 | |||
| Nodal stage (%) | 0.564 | |||
| N0 | 114 | 53 (46.5) | 61 (53.5) | |
| N1 | 91 | 49 (53.8) | 42 (46.2) | |
| N2 | 32 | 13 (40.6) | 19 (59.4) | |
| N3 | 14 | 5 (35.7) | 9 (64.3) | |
| Missing | 2 | |||
| Metastasis (%) | 0.947 | |||
| M0 | 225 | 106 (47.1) | 119 (52.9) | |
| M1 | 13 | 6 (46.2) | 7 (53.8) | |
| Missing | 15 | |||
Abbreviations: ER, estrogen receptor; FISH, fluorescence in situ hybridization; Her2, human epidermal growth factor receptor 2; PR, progesterone receptor.