Fig. 3.

Total proteome and Metacore analysis of PDI-poor or PDI-rich plasma. Samples from individuals with PDI-poor plasma (n = 3) or PDI-rich plasma (n = 3) were submitted to shotgun mass spectrometry profiling analysis to identify proteins differentially expressed in each case. There were 65 proteins differentially upregulated in PDI-poor plasma samples and 60 proteins differentially upregulated in PDI-rich plasma samples. Further analysis using Metacore software revealed enrichment in several pathways and biological processes (p < 0.05).