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. 2019 Mar 19;7:e6611. doi: 10.7717/peerj.6611

Figure 6. A visual display of the gene network connected to ESR1/PIK3CA/AKT1/MAPK1 in prostate adenocarcinoma (based on the NEPC study, Nat Med 2016) (Beltran et al., 2016).

Figure 6

(A) Cross-cancer alteration summary for ESR1/PIK3CA/AKT1/MAPK1 mined from the cBioPortal for Cancer Genomics. Multidimensional genomic details are shown for seed genes ESR1, PIK3CA, AKT1, and MAPK1. A darker shade of red indicates increased frequency of alteration in prostate cancer. (B) Neighboring genes connected to the four query genes, filtered by alterations (45%).