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. Author manuscript; available in PMC: 2019 Apr 8.
Published in final edited form as: Nat Genet. 2018 Oct 8;50(11):1501–1504. doi: 10.1038/s41588-018-0243-4

Figure 3. S. cerevisiae thermotolerance alleles are necessary and sufficient for growth at high temperature.

Figure 3.

a, Each bar reports mean growth efficiency at 39°C, measured in liquid culture assays (n = 8-12 cultures), of an S. cerevisiae strain harboring the S. paradoxus allele at the indicated RH-seq hit locus, relative to the analogous quantity for wild-type S. cerevisiae. b, Data are as in a, except that each bar reports results from a S. paradoxus strain harboring the S. cerevisiae allele at the indicated locus, normalized to wild-type S. paradoxus. In a given panel, the top and bottom dotted lines report the relative efficiency of wild-type S. cerevisiae and S. paradoxus, respectively. *, p ≤ 0.036; **, p ≤ 0.001, one-sample, one-tailed t-test; individual measurements are reported as circles. See Supplementary Table 1 for exact p-values and sample numbers.