Table 2.
Effect of treatment versus placebo on variables.
| Variable (unit) | Intervention |
Placebo |
||||||
|---|---|---|---|---|---|---|---|---|
| Baseline | After 45 days | Δ change (pre-post) | p-value | Baseline | After 45 days | Δ change (pre-post) | p-value | |
| Aerophagia (SCORE) | 0.04 (0.95) | 0.08 (0.58) | 0.04 (−0.53; 0.45) | 0.86 | 0,04 (0,47) | 0.00 (0.30) | −0,04 (−0.2; 0.3) | 0.71 |
| Diarrhea ((SCORE) | 0.08 (0.41) | 0.17 (0.38) | 0.08 (−0.33; 0.16) | 0.49 | −0.04 (0.71) | 0.09 (0.60) | 0,13 (−0.5; 0.22) | 0.45 |
| Constipation ((SCORE) | 0.00 (0.83) | 0.00 (0.66) | 0.00 (−0.47; 0.47) | 1 | −0.30 (0.88) | 0.04 (0.64) | 0,35 (−0.9; 0.16) | 0.18 |
| Abdominal pain ((SCORE) | 0.00 (0.66) | −0.17 (0.76) | −0.17 (0.28; 0.61) | 0.45 | 0.09 (0.29) | 0.09 (0.29) | 0 (−0.13; 0.13) | 1 |
| Diarrhea-Costipation (SCORE) | - 0.08 (0.28) | −0.08 (0.50) | 0.00 (−0.25; 0.25) | 1 | 0.09 (0.52) | −0.04 (0.48) | −0.13 (−0.17; 0.43) | 0.38 |
| sIgA (μg/ml) | 137.52 (70.87) | 149.43 (120.70) | 11.91 (−41.17; 17.35) | 0.42 | 149.64 (109.46) | 162.06 (146.73) | 12,41 (−38.9; 16.07) | 0.35 |
| sAA (ng/gr of feces) | 59.1 (30.19) | 75.31 (42.89) | 16.21 (−52.87; 20.45) | 0.32 | 84.18 (25.41) | 88.42 (29.46) | 4.24 (−17.27; 8.80) | 0,50 |
| CgA (pg/gr of feces) | 1848.19 (1027.56) | 2138.72 (1148.22) | 290.52 (−806.74; 225,69) | 0.26 | 1366.36 (786.22) | 1702.18 (1083.46) | 335,82 (−765.27; 93.62) | 0.12 |
| Cortisol (ng/gr of feces) | 5.72 (2.39) | 5.59 (3.12) | −0.13 (−24.50; 6.88) | 0.76 | 5.87 (2.61) | 5.42 (2.47) | −0.45 (−22.14; 64.8) | 0.13 |
| IgA (μg/gr of feces) | 30.29 (35.64) | 39.10 (40.26) | 8.81 (−0.7; 0.25) | 0.27 | 50.91 (142.34) | 29.58 (33.42) | −21.33 (−0.2; 0.15) | 0.33 |
| IL8 (pg/gr of feces) | 0.29 (1.02) | 0.51 (1.28) | 0.22 (−21.47; 2.57) | 0.35 | 0.24 (1.05) | 0.26 (1.13) | 0.02 (−33; 31.77) | 0.79 |
| IL10 (pg/gr of feces) | 12.57 (16.20) | 22.02 (35.58) | 9.45 (−1.10; 0.46) | 0.12 | 40.90 (80.42) | 41.75 (111.60) | 0.85 (−0.94; 1.55) | 0.96 |
| TNFa (pg/gr of feces) | 0.96 (2.43) | 1.72 (3.10) | 0.77 (−0.68; 2.06) | 0.22 | 1.79 (3.49) | 1.49 (2.77) | −0.30 (−1.77; 0.75) | 0.63 |
| NK 1:10 (%lysis) | 4.08 (4.84) | 3.39 (6.10) | −0.69 (−0.66; 2.67) | 0.32 | 2.43 (3.04) | 2.95 (3.71) | 0.51 (−2.47; 1.69) | 0.42 |
| NK 1:30 (%lysis) | 7.08 (8.77) | 6.08 (8.09) | −1 (−1.07; 3.10) | 0.23 | 4.90 (6.21) | 5.28 (5.67) | 0.39 (−2.53; 3.8) | 0.71 |
| NK 1:100 (%lysis) | 11.12 (12.48) | 9.67 (9.70) | −1.45 (−4.42; 3,32) | 0.25 | 9.94 (10.20) | 9.31 (8.95) | −0.63 (−9.23; 8.34) | 0.69 |