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Primary bile acid biosynthesis pathway affected by HFD. The bar graphs represent two metabolites, 3β, 7α-dihydroxy-5-cholestenoate and cholic acid, altered significantly between WTNF and WTHF (*q<0.1, **q<0.05). The gene cyp7b1 was found severely down-regulated (FC threshold=1.5) in WTHF shown in light blue boxes. cyp27a1 and hsd3b7 were down-regulated as well but not included in the criteria (FC threshold=1.5).
