Table 2.
Fold change of metabolites and genes for each pathway and group, respectively
| Pathway (Group) | Phenotype | Name | Fold Change |
|---|---|---|---|
| Primary bile acid biosynthesis (WTNF vs WTHF) | Metabolite (m/z) | Cholic acid (391.28) | 0.3071 |
| 3β, 7α-Dihydroxy-5-cholestenoate (433.33) | 0.1501 | ||
| Gene | cyp7b1 | 0.5040 | |
| Retinoic acid metabolism (WTHF vs CKOHF) | Metabolite (m/z) | all-trans-4-Hydroxy-retinoic acid (334.23) | 2.4388 |
| all-trans-4-Oxo-retinoic acid (332.22) | 2.8720 | ||
| Gene | cyp3a41b | 1.5344 | |
| Linolenic acid metabolism(WTHF vs CKOHF) | Metabolite (m/z) | α/γ-Linolenic acid (296.25) | 2.1972 |
| Eicosapentaenoic acid (320.25) | 2.0151 | ||
| Thromboxane A2 (335.22) | 3.3668 | ||
| Gene | ptgs1 | 1.5893 | |
| tbxas1 | 2.0721 |