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. 2018 Dec 19;60(2):221–227. doi: 10.1093/jrr/rry089

Table 2.

Grade ≥2 late toxicities

Grade 2/3 toxicity P
2.0 Gy/day 2.1 Gy/day 2.2 Gy/day
Genitourinary
 Urinary frequency 1/0 1/0 5/0
 Hematuria 2/0 2/2 0/1
 Urinary retention 0/1 2/0 1/0
 Urinary incontinence 1/0 0/0 4/0
 Totala 7.2%b 7.4%c 7.1%d 0.98e
Gastrointestinal
 Rectal hemorrhage 9/0 11/3 12/0
 Totala 12.4%b 14.1%c 7.9%d 0.29e

aCumulative incidence of Grade ≥2 late genitourinary/gastrointestinal toxicity. bIncidence at 10 years. cIncidence at 8 years. dIncidence at 6 years. eExamined by logrank test.