Table 1.
Clinical criteria | Immunologic criteria |
---|---|
Acute cutaneous lupus | Antinuclear antibody |
Chronic cutaneous lupus | Anti-DNA antibody |
Oral or nasal ulcers | Anti-Smith antibody |
Non-scarring alopecia | Antiphospholipid antibody |
Arthritis | Low complements (C3, C4 or CH50) |
Serositis | Direct Coombs’ test in the absence of hemolytic anemia |
Renal disease | |
Neurologic disease | |
Hemolytic anemia | |
Leucopenia | |
Thrombocytopenia |
Requirements: ≥ 4 criteria (at least 1 clinical and 1 laboratory criteria) or biopsy-proven lupus nephritis with positive ANA or anti-DNA