Table 4.
The allele and genotype distribution of rs892066 (C/G) in the T2DM patients and control subjects
| Genotype | Controls (138) | T2DM patients (150) | P a | OR (95% CI)a | P b | OR (95% CI)b |
|---|---|---|---|---|---|---|
| rs892066 (C/G) | ||||||
| CC | 92 (66.6%) | 98 (65.3%) | 0.9 | |||
| CG | 38 (27.7%) | 42 (28.1%) | 0.89 | 1.03 (0.61‐1.75) | 0.82 | 0.94 (0.54‐01.61) |
| GG | 8 (5.7%) | 10 (6.6%) | 0.74 | 1.17 (0.44‐3.1) | 0.93 | 0.96 (0.35‐2.63) |
| Recessive model | ||||||
| CC + GC | 130 (94.3%) | 140 (93.4%) | ||||
| GG | 8 (5.7%) | 10 (6.6%) | 0.7 | 1.16 (0.44‐3.03) | 0.9 | 1.01 (0.37‐2.7) |
| Dominant model | ||||||
| GG + GC | 46 (33.4%) | 52 (34.7%) | 0.8 | 1.06 (0.65‐1.72) | 0.84 | 0.94 (0.57‐1.57) |
| CC | 92 (66.6%) | 98 (65.3%) | ||||
| Allele | ||||||
| G | 54 (19.5%) | 62 (20.6%) | ||||
| C | 222 (80.5%) | 238 (79.4%) | 0.74 | 1.07 (0.71‐1.61) | ||
a
P and OR calculated by chi‐square test.
b
P and OR calculated by logistic regression test after adjustment for Age, BMI, and lipid profile.