Table 2. Disease and medication-related variables regarding to adherence rate.
| Variable | Overall | Low adherence | Medium/High adherence | P |
|---|---|---|---|---|
| Disease duration in years | 5.89±4.87 | 5.51±4.06 | 6.27±5.54 | .7431 |
| < 1 year | 20 (7.7) | 10 (7.8) | 10 (7.7) | .9552 |
| 1–5 years | 125 (48.3) | 63 (48.8) | 62 (47.7) | |
| ≥ 5 years | 114 (44.0) | 56 (43.4) | 58 (44.6) | |
| Number of oral 5-ASA / day | 3.69±1.78 | 3.78±1.74 | 3.61±1.82 | .5461 |
| 1–5 | 205 (79.2) | 100 (77.5) | 105 (80.8) | .5202 |
| ≥ 6 | 54 (20.8) | 29 (22.5) | 25 (19.2) | |
| Times of oral 5-ASA | ||||
| Once a day | 124 (47.9) | 63 (48.8) | 61 (46.9) | .7582 |
| Twice or 3 times a day | 135 (52.1) | 66 (51.2) | 69 (53.1) | |
| 5-ASA suppository | ||||
| Yes | 71 (27.4) | 36 (27.9) | 35 (26.9) | .8592 |
| No | 188 (72.6) | 93 (72.1) | 95 (73.1) | |
| Anti-TNF | ||||
| Yes | 40 (15.4) | 19 (14.7) | 21 (16.2) | .7512 |
| No | 219 (84.6) | 110 (85.3) | 109 (83.8) | |
| Azathioprine use | ||||
| Yes | 49 (18.9) | 22 (17.1) | 27 (20.8) | .4452 |
| No | 210 (81.1) | 107 (82.9) | 103 (79.2) | |
| Types of 5-ASA | ||||
| Mezavant | 62 (23.9) | 24 (18.6) | 38 (29.2) | .2562 |
| Pentasa slow | 97 (37.5) | 51 (39.5) | 46 (35.4) | |
| Asacol dr | 76 (29.3) | 41 (31.8) | 35 (26.9) | |
| Colazal | 24 (9.3) | 13 (10.1) | 11 (8.5) | |
| Disease extent at diagnosis | ||||
| Proctitis | 90 (34.7) | 47 (36.4) | 43 (33.1) | .7102 |
| Left side colitis | 111 (42.9) | 52 (40.3) | 59 (45.4) | |
| Extensive colitis | 58 (22.4) | 30 (23.3) | 28 (21.5) | |
| Presence of comorbidities | ||||
| Yes | 69 (26.6) | 29 (22.5) | 40 (30.8) | .1312 |
| No | 190 (73.4) | 100 (77.5) | 90 (69.2) | |
| Number of UC flare up in past year | 0.45±0.93 | 0.44±0.90 | 0.46±0.97 | .9101 |
| 0 | 192 (74.1) | 95 (73.6) | 97 (74.6) | .9232 |
| 1–2 | 52 (20.1) | 27 (20.9) | 25 (19.2) | |
| ≥ 3 | 15 (5.8) | 7 (5.4) | 8 (6.2) |
Values are either mean±SD or frequency with percentage in parentheses.
1 P values were derived from Mann-Whitney’s U test.
2 P values were derived from chi-square test.
Shapiro-Wilk’s test was employed for test of normality assumption.