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. 2019 Mar 22;14(3):e0213397. doi: 10.1371/journal.pone.0213397

Fig 2. In vitro assays of 111In-labeled 3-arm DOTA-α-MSH and 111In-labeled 4-arm DOTA-α-MSH in B16-F1 melanoma cells and 4T1 breast cancer cells after 180 min of incubation in the presence or absence (control) of α-MSH.

Fig 2

The accumulation of both radiotracers in cells was significantly inhibited by α-MSH. In 4T1 cells with low MC1-R expression, no significant accumulation and no inhibition effect were observed for either radiotracer. **P < 0.01 vs. control. https://doi.org/10.6084/m9.figshare.7697882.