Figure 1.

Overexpression of cno induces mixed effects. (A‐H) Immnostaining of MMP1, β‐gal, cleaved caspase3, or TUNEL staining in wing discs expressing ptc‐Gal4 UAS‐GFP/+; UAS‐GFP/+ (A, E and G), ptc‐Gal4 UAS‐GFP/+; UAS‐cno/+ (B, F and H), ptc‐Gal4 UAS‐GFP/+; UAS‐GFP/puc‐lacZ (C) or ptc‐Gal4 UAS‐GFP/+; UAS‐cno/puc‐lacZ (D). White dashed lines indicate the edges of the wing discs. Note the reduced disc size in the presence of enhancer‐trapped puc‐lacZ, which additionally increases JNK activity due to the removal of one copy of puc