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. 2018 Oct 5;52(1):e12513. doi: 10.1111/cpr.12513

Table 1.

Functional characterizations of ZFAS1 in multiple human cancers

Cancer types Expression Role Functional role Related genes References
Colorectal cancer Upregulated Oncogenic Cell proliferation migration, invasive, metastasis, cell cycle control, cell antiapoptosis miR‐484
miR‐590‐3p
p53 and EMT signalling pathway
21, 22, 23, 24
Gastric cancer Upregulated Oncogenic Cell proliferation, cell antiapoptosis, cell migration and metastasis, cell cycle control EMT, KLF2, EZH2, NKD2 25, 26, 27
Hepatocellular carcinoma Upregulated Oncogenic Cell invasion and tumour metastasis miR‐150, ZEB1, MMP14, and MMP16 28
Glioma Upregulated Oncogenic Cell proliferation, migration, and invasive Notch and EMT signalling pathway 30, 31
Osteosarcoma Upregulated Oncogenic Cell proliferation, migration and invasion, cell antiapoptosis, cell cycle control miR‐200b/c, miR‐486, BMI1, ZEB2 32, 33
Ovarian cancer Upregulated Oncogenic Cell proliferation migration, chemoresistance miR‐150‐5p, Sp1 34, 35
Acute myeloid leukaemia Upregulated Oncogenic Cell proliferation, cell antiapoptosis, cell cycle control 36
Nonsmall cell lung cancer Upregulated Oncogenic 37
Oesophageal squamous cell carcinoma Upregulated Oncogenic 29