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. Author manuscript; available in PMC: 2020 Mar 21.
Published in final edited form as: Mol Cell. 2019 Feb 12;73(6):1204–1216.e4. doi: 10.1016/j.molcel.2019.01.010

Figure 6.

Figure 6.

PARN knockdown increases sensitivity of HeLa cells to chemotherapeutic agents. A) Representative bright field images of control and PARN knockdown HeLa cells at indicated time points after Doxorubicin treatment (Scale bar: 300 μm). B) and C) Viable cells under various knockdown and treatment conditions as measured using trypan blue staining assay (Average +/− S.D for three biological replicates). D) Representative western blots for p53 and PARN protein levels in HCT116 cells with or without Dox or EP treatment (Average +/− S.D. for four biological replicates). E) Representative western blots for p53 and PARN protein levels in U87 cells with or without Dox or EP treatment (Average +/− S.D. for five biological replicates for Dox treatment and three biological replicates for EP treatment).