Table 2.
Associations between change in MDS and change in ectopic fat depots (adjusted mean and 95% confidence interval)
| Quartile ΔMDS |
||||||
|---|---|---|---|---|---|---|
| Q1 | Q2 | Q3 | Q4 | Per SD Increase in ΔMDS | ||
| Median ΔMDS | −4 | −1 | 1 | 5 | P-value | |
| Change in VAT volume, cm3 | ||||||
| Model 1 | 713 (645, 781) | 655 (596, 714) | 632 (559, 706) | 598 (537, 658) | −47 (−82, −13) | 0.007 |
| Model 2 | 715 (646, 784) | 658 (599, 716) | 631 (557, 704) | 595 (533, 657) | −50 (−86, −14) | 0.007 |
| Change in SAT volume, cm3 | ||||||
| Model 1 | 546 (471, 621) | 529 (464, 594) | 544 (462, 625) | 462 (395, 529) | −37 (−75, 1) | 0.06 |
| Model 2 | 563 (486, 639) | 535 (470, 600) | 545 (464, 626) | 442 (373, 510) | −52 (−92, −12) | 0.01 |
| Change in VSR | ||||||
| Model 1 | 0.11 (0.09, 0.13) | 0.10 (0.09, 0.12) | 0.09 (0.07, 0.11) | 0.08 (0.07, 0.10) | −0.01 (−0.02, 0.00) | 0.008 |
| Model 2 | 0.11 (0.09, 0.13) | 0.10 (0.08, 0.12) | 0.09 (0.07, 0.11) | 0.09 (0.07, 0.11) | −0.01 (−0.02, 0.00) | 0.04 |
| Change in PAT volume, cm3 | ||||||
| Model 1 | –0.7 (−3.0, 1.5) | −1.9 (−3.8, 0.0) | −4.1 (−6.5, −1.7) | −3.1 (−5.1, −1.1) | −1.2 (−2.3, 0.0) | 0.046 |
| Model 2 | 0.8 (−4.1, 5.7) | −0.4 (−5.1, 4.3) | −2.7 (−7.5, 2.1) | −1.8 (−6.5, 2.9) | −1.3 (−2.4, −0.1) | 0.04 |
Model 1 adjusted for sex, age, baseline adipose tissue (e.g., baseline VAT for ΔVAT or baseline VSR for ΔVSR), baseline MDS, baseline energy intake, baseline physical activity, and baseline smoking status; Model 2 adjusted for model 1 covariates plus baseline BMI, change in energy intake, physical activity, and smoking status. In model 2, we also adjusted for baseline SAT in analysis for ΔVAT and baseline VAT in analysis for ΔSAT. BMI=Body Mass Index; VAT=Visceral Adipose Tissue; SAT= Abdominal Subcutaneous Adipose Tissue; VSR=VAT to SAT Ratio; PAT=Pericardial Adipose Tissue; MDS=Mediterranean-style diet score; SD=Standard Deviation