Table 1.
Stress paradigms in preclinical and clinical research included in the present review.
Paradigm | Indication | Reference in manuscript |
---|---|---|
Preclinical | ||
Learned helplessness | Depression | Vengeliene et al., 2005 |
SDPSa | Depression | Riga et al., 2014 |
Predator odor | Psychological stress/PTSDb | Cozzoli et al., 2014 |
Tail suspension | Psychological stress/acute stress | Cozzoli et al., 2014 |
Restraint | Physical stress/acute stress | Cozzoli et al., 2014 |
Foot shock | Physical stress/acute stress | Cozzoli et al., 2014; Le et al., 2005; Zorrilla et al., 2013 |
Tail pinch | Physical stress/acute stress | Cozzoli et al., 2014 |
Noise stress | Mild stress exposure/acute stress | Arnsten and Goldman-Rakic, 1998 |
Yohimbinee |
Pharmacologic stress/acute stress |
Bertholomey et al., 2016; Le et al., 2005; Zorrilla et al., 2013 |
Clinical | ||
CRFc/cortisol administration | Increase pituitary-adrenal axis response | Heim et al., 2001 |
Citalopram stimulation test | Assess neuroendocrine reaction | Anthenelli et al., 2018 |
Combined dexamethasone/CRFc test | Assess glucocorticoid feedback loop | Schwandt et al., 2016; Anthenelli et al., 2018 |
Cosyntropin | Assess adrenocortical response | Adinoff et al., 2010 |
Combined Cosyntropin/dexamethasone | Assess neuroendocrine feedback | Adinoff et al., 2010 |
Trier Social Stress Test | Psychological stress | Kwako et al., 2015 |
Imagery Scripts | Psychological stress | Chaplin et al., 2008; McKee et al., 2011; Seo et al., 2011; Kwako et al., 2015 |
Emotionally arousing films | Arouse negative emotions | Cahill et al., 2001 |
IAPSd | Induce highly charged emotions | Garavan et al., 2001 |
Public speaking challenge | Psychological stress | Bernardy, 1995; Lovallo et al., 2000; Sorocco et al., 2006 |
Mental arithmetic task | Psychological stress | Bernardy et al., 1996; Bernardy, 1995; Errico et al., 2002; Sorocco et al., 2006 |
SDPS = social defeat-induced persistent stress.
PTSD = post-traumatic stress disorder.
CRF = corticotropin-releasing factor.
IAPS = International Affective Picture System.
= also used in clinical paradigms; self-report questionnaires/measures are not described above.