. Author manuscript; available in PMC: 2019 Mar 23.

Published in final edited form as: J Am Chem Soc. 2018 Nov 14;140(47):16140–16151. doi: 10.1021/jacs.8b08711

Table 1.

Minimum Biofilm Eradication Concentrations (MBECs, μM)^a and Minimum Inhibitory Concentrations (MICs, μM)^b

MBECs					MICs
strain	V	V–r8 (TFA)	r8	V + r8	V	V–r8 (TFA)	r8	V + r8
MISSA (29213)	≥500	20 (16–25)	>80	80 (63–125)	0.50 (0.50–0.63)	1.8 (1.0–2.0)	60 (40–80)	0.50
MRSA (USA400 MW2)	≥500	10 (6–26)	>80	>20 (20–>80)	0.50 (0.31–0.63)	0.94 (0.63–1.0)	20	0.50
MRSA (USA300 LAC)	≥400	9.5 (3–16)	>80	16 (10–40)	0.50 (0.31–0.50)	2.0 (1.8–2.0)	40	0.50

Median MBEC values from two to six independent experiments, where ranges are given in parentheses. For V and r8, MBEC values often exceeded the highest concentrations tested.

Median MIC values from two to seven independent experiments, where ranges are given in parentheses.