Table 1.
Medians and interquartile ranges for unconjugated ZEN, zeranol and total mycoestrogens according to selected characteristic among the Jersey Girl Study participants included in these analyses (n = 163)
| Characteristic | n (%) | ZEN Median(IQR) (ng/ml) |
Zeranol Median(IQR) (ng/ml) |
Total Mycoestrogen Median(IQR)(ng/ml) |
|---|---|---|---|---|
| Girl’s Race | ||||
| White | 146 (90) | 0.15 (0.35) | 0.04 (0) | 0.30 (0.71) |
| non-White | 13 (8) | 0.31 (0.66) | 0.10 (0.20) | 0.53 (1.66) |
| Missing | 4 (2) | 1.10 (1.28) | 0.04 (0.17) | 1.25 (1.74) |
| p-value | 0.47 | 0.23 | 0.26 | |
| BMI at Menarche for Age and Gender (CDC)a | ||||
| Underweight | 9 (6) | 0.04 (0) | 0.04 (0) | 0.30 |
| Healthy Weight | 101 (62) | 0.23 (0.28) | 0.04 (0) | 0.24 (0.51) |
| Overweight | 16 (10) | 0.10 (0.36) | 0.04 (0) | 0.26 (0.66) |
| Obese | 12 (7) | 0.30 (0.65) | 0.04 (0) | 0.15 (0.41) |
| Missing | 25 (15) | 0.23 (0.41) | 0.04 (0) | 0.30 (0.39) |
| p-value | 0.49 | 0.52 | 0.77 | |
| Age at Menarche (years) | ||||
| ≤ 11.8b | 59 (22) | 0.22 (0.43) | 0.04 (0) | 0.31 (0.70) |
| > 11.8 | 104 (63) | 0.14 (0.32) | 0.04 (0) | 0.32 (0.89) |
| Missing | 25 (15) | 0.24 (0.39) | 0.04 (0) | 0.37 (0.67) |
| p-value | 0.49 | 0.53 | 0.33 | |
| Weight at Menarche (Kg)c | ||||
| ≤ 46.5 | 46 (28) | 0.22 (0.49) | 0.04 (0.05) | 0.30 (0.86) |
| > 46.5–52.6 | 46 (28) | 0.09 (0.30) | 0.04 (0) | 0.31 (0.59) |
| > 52.6 | 46 (28) | 0.09 (0.54) | 0.04 (0) | 0.26 (0.87) |
| Missing | 25 (15) | 0.22 (0.39) | 0.04 (0) | 0.40 (0.83) |
| p-value | 0.64 | 0.53 | 0.27 | |
| Height at Menarche (cm)c | ||||
| ≤ 156.2 | 49 (30) | 0.27 (0.56) | 0.04 (0.07) | 0.49 (0.90) |
| > 156.2–162.6 | 52 (32) | 0.17 (0.36) | 0.04 (0) | 0.28 (0.78) |
| > 162.6 | 37 (23) | 0.04 (0.29) | 0.04 (0) | 0.12 (0.44) |
| Missing | 25 (15) | 0.22 (0.39 | 0.04 (0) | 0.40 (0.83) |
| p-value | 0.04 | 0.04 | 0.07 | |
Notes: p values from Kruskal-Wallis tests, levels below the LOD were replaced by [LOD/√2] (medians = 0.04 are <LOD), and missing n included girls lost to follow-up and those with no menses yet
Total Mycoestrogen [aglycones]: sum of zearalenone, zeranol, α-zearalenol, β-zearalenol, β-zearalanol, and zearalanol, ZEN Zearalenone, IQR interquartile range
aUnderweight (<5th Percentile), Healthy Weight (5th - <85th percentile), Overweight (85th- < 95th percentile), Obese (>95th percentile) percentile)
b25th percentile of age at menarche distribution among all girls with recorded age at menarche
cCategories are based on tertiles for weight and height distribution at the follow-up date when menarche was reported