Table 2.
Cox regression models for the association between mycoestrogen exposure (ng/ml) and time to menarche in the Jersey Girl Study
| Mycoestrogen (ng/ml) | n | Unadjusted HR (95%CI) |
Adjusteda HR(95%CI) |
Adjustedb HR(95%CI) |
|---|---|---|---|---|
| ZEN | ||||
| < LOD | 62 | Ref | Ref | Ref |
| > LOD | 77 | 1.20 (0.70–2.08) | 1.11 (0.78–2.0) | 0.99 (0.93–1.05) |
| Zeranol | ||||
| < LOD | 108 | Ref | Ref | Ref |
| > LOD | 31 | 0.35 (0.06–1.89) | 0.41 (0.10–1.85) | 0.35 (0.06–2.00) |
| Total Mycoestrogen | ||||
| < LOD | 31 | Ref | Ref | Ref |
| > LOD | 108 | 1.00 (0.96–1.04) | 0.94 (0.89–1.00) | 0.99 (0.95–1.04) |
HR Hazard Ratio, CI Confidence Interval, LOD limit of detection (0.05 ng/ml), REF: reference group, Total Mycoestrogen [aglycones]: sum of zearalenone, zeranol, α-zearalenol, β-zearalenol, β-zearalanol, and zearalanol, ZEN: Zearalenone
aAdjusted for family income
bAdjusted for family income and body mass index at menarche