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. 2019 Mar 23;12:25. doi: 10.1186/s13048-019-0500-x

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — a Partial least square discriminant analysis (PLS-DA) models to discriminate Controls (CTRL, yellow circles), PCOS patients at enrolment (PCOS-T0, green circles) and PCOS patients after 3-months treatment (PCOS-T1, purple circles). The explained variance of each component is shown in parentheses on the corresponding axis. b The 15 top-scoring VIP metabolites (VIP-score ≥ 1.5) are shown. The colored boxes on the right indicate the relative amount of the corresponding metabolite in each group under study