Table 2.
Risk factors predisposing to acute kidney injury (AKI)
| Parameters | AKI group (n = 31) | Non-AKI group (n = 146) | p value |
|---|---|---|---|
| Age in years | 50 (21-77) | 55 (26-84) | 0.02 |
| Gender | 26 : 5 (83% : 17%) | 128 : 18 (91% : 9%) | 0.56 |
| Co morbid states | |||
| Diabetes mellitus | 12 (38%) | 66 (47%) | 0.67 |
| Hypertension | 5 (16%) | 24 (17%) | |
| Coronary artery disease | 1 (3.2%) | 10 (7%) | |
| Hypothyroidism | 3 (9.6%) | 6 (4.2%) | |
| Others | 0 (0%) | 5 (3.5%) | |
| Combined | 6 (19%) | 30 (21%) | |
| Etiology | |||
| Alcohol | 15 (48%) | 50 (35%) | 0.38 |
| NASH/cryptogenic | 11 (35%) | 72 (51%) | |
| Hepatotropic viruses | 4 (12%) | 22 (15%) | |
| Others | 1 (3.2%) | 2 (1.4%) | |
| CTP class | |||
| B | 2 (6.4%) | 38 (27%) | 0.017 |
| C | 29 (93%) | 108 (77%) | |
| MELD | |||
| MELD score | 24 (14-40) | 19 (8-40) | < 0.0001 |
| Baseline serum albumin (mean and SD) | |||
| Serum albumin (gm/dl) | 2.78 (0.45) | 2.73 (0.38) | 0.52 |
| Cirrhosis-related complications | |||
| SBP | 20 (64%) | 78 (55%) | 0.35 |
| HE | 26 (83%) | 109 (77%) | 0.46 |
| GI bleeding | 19 (61%) | 65 (46%) | 0.13 |
| Sepsis | 16 (51%) | 67 (47%) | 0.68 |
| Renal dysfunction | 22 (70%) | 46 (32%) | 0.0001 |
| HCC | 0 (0%) | 3 (2.1%) | Not applicable |
CTP – Child-Turcotte-Pugh, MELD – Model For End-Stage Liver Disease, NASH – nonalcoholic steatohepatitis, SBP – spontaneous bacterial peritonitis, HE – hepatic encephalopathy, GI – gastrointestinal, HCC – hepatocellular carcinoma