FIG 2.

IDR-1018 inhibits bacterial biofilm formation and eradicates preformed biofilms in Gram-negative and Gram-positive bacteria. Gram-positive and -negative bacterial biofilm formation was monitored for up to 3 days after treating the surface with IDR-1018 at sub-MICs. Biofilm eradication was evaluated 2 days after the flow cell surface came into contact with the bacteria. Bacterial presence was tested using live/dead staining using confocal microscopy. (Adapted from reference 33 [published under a Creative Commons license].)