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Various surface modifications of liposomes. Structure, composition, and surface modifications increase the utility of liposomes as drug carriers. A multilamellar (multiple lipid bilayer) liposome is more useful for controlled drug release. Surface modifications such as positive charge, PEGylation, and ligand conjugation are governed for the liposome to penetrate the biofilm better, protect it from degradation by proteases, and selectively bind to the target molecule, respectively.
