Evolution of the regulatory regions associated with pterin- and carotenoid-based coloration in the genus Podarcis. (A) Median-joining genealogies of the genomic regions associated with coloration upstream of SPR (Left) and BCO2 (Right) from common wall lizards from the Pyrenees. The dashes on branches indicate the number of observed mutations. (B) NeighborNet trees of the genomic regions associated with coloration upstream of SPR (Left) and BCO2 (Right) combining common wall lizards from the Pyrenees and six other species in the genus Podarcis. Haplotypes are colored orange, yellow, or white, indicating the color morph of the individual. For representation purposes, only a subset of the sequences is presented. (C) Pairwise nucleotide differences between haplotypes within species for SPR (orange), BCO2 (yellow), and 31 random loci (black). The average is indicated by a green circle. (D) Pairwise nucleotide differences between haplotypes of the common wall lizard and other Podarcis species for SPR (orange), BCO2 (yellow), and 31 random loci (black). The contrasts involving other species are presented in SI Appendix, Fig. S7.