Table 1.

Pharmacokinetic parameters of insulin in diabetic rats

Formulation	Dose, IU/kg	AUC, μIU⋅h/mL	F, %
Insulin sol (s.c.)	5	210.30 ± 27.29	100
Insulin sol (oral)	30	15.54 ± 10.63	1.23
Lip1	30	75.92 ± 38.09	5.95
Lip4	30	172.04 ± 13.19	13.65
Lip6	30	122.18 ± 5.59	9.68

AUC, Area under the curve; F, relative bioavailability.