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. Author manuscript; available in PMC: 2019 Mar 23.
Published in final edited form as: Nature. 2017 May 3;545(7653):181–186. doi: 10.1038/nature22324

Extended Data Figure 3. Effects of thalamic muscimol infusions on behavior.

Extended Data Figure 3

a. Muscimol infusion locations (red crosses) near VM/VAL. Sites from left (n = 3) and right (n = 3) hemispheres were mapped onto the left hemisphere.

b. Small muscimol infusion (1.5-5 ng) near VM/VAL produced ipsilateral bias. Left, performance change in contra-trials after muscimol infusion. Right, performance change in ipsi-trials after muscimol infusion. Each line represents an infusion site (n = 6, same mice as in a). *, P < 0.05.

c. Muscimol infusion locations in the anterior part of the thalamus (red crosses). Sites from left (n = 2) and right (n = 2) hemispheres were mapped onto the left hemisphere.

d. Muscimol infusions in the anterior part of the thalamus (∼ 0.3 – 0.8 mm anterior to VM/VAL; same mice as in c). Note that much higher muscimol concentrations (10 times of those used near VM/VAL), did not affect behavior.

e. Muscimol infusion locations in the dorsal part of the thalamus (red crosses). Sites from left (n = 2) and right (n = 2) hemispheres were mapped onto the left hemisphere.

f. Muscimol infusions in the dorsal part of the thalamus (∼ 0.2 - 0.5 mm dorsal to medial dorsal thalamus, same mice as in e). Note that much higher muscimol concentrations (10 times of those used near VM/VAL), did not affect behavior.