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. 2018 Dec 24;2018:8972572. doi: 10.1155/2018/8972572

Figure 3.

Figure 3

Expanded frequency of circulating plasma cells in GD patients. Human PBMCs from GD patients (BT: 36; AT: 21) and 20 HC were stained with anti-CD19, anti-CD38, and anti-CD27. (a) The cells were gated initially on lymphocytes and then on CD19+B cells; afterwards, the numbers of CD27highCD38high PCs were analyzed by flow cytometry. (b) Changes in PCs in GD patients. (c) Relation of PC proportions and serum TPO-Ab levels in GD patients. (d) Relation of Tfh2 subset proportions with PCs in GD patients. (e) The correlation between the proportions of PCs and ICOS+Tfh cells in GD patients. (f) The correlation between the proportions of PCs and PD-1+Tfh cells in GD patients. ∗p < 0.05, ∗∗p < 0.01, and ∗∗∗p < 0.001; ns: no significant difference.